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                  <text>Sinus Tumors
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Bighorn sheep sinus tumors are an infectious disease that causes thickening
of the sinus lining or solid masses in the upper respiratory sinuses.

Species Affected in Colorado
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Rocky Mountain bighorn sheep
Desert bighorn sheep
California bighorn sheep
Mountain goats

What to Look For
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Thickened lining of the sinuses of the skull and
horns.
Solid masses filling the sinus cavities.
Masses may be soft and gelatinous, hard and
bony, or both.
Masses invade bone and may cause horn or
facial abnormalities.
Thick nasal exudates, especially with
concurrent bacterial infections.

Bighorn sheep sinus tumor filling frontal sinus on right
side of image. Photo credit Karen Fox, CPW.

Cause and Transmission

The cause of bighorn sheep sinus tumors remains unknown, although experimental transmission of the disease
suggests an infectious, likely viral, etiology. Sinus tumors appear to prevent normal clearance of pathogens from
the upper respiratory tract, enhancing carriage (and likely shedding) of other pathogens including Mycoplasma
ovipneumoniae and Pasteurellaceae. Colorado herds that struggle with recurrent lamb pneumonia often have
particularly high occurrence of sinus tumors in adults, and presence of tumors may enhance spread of pneumoniacausing bacteria to lambs. Experimental transmission of sinus tumors to domestic sheep has been demonstrated.

References
Fox, KA, SK Wootton, AJ Marolf, NM Rouse, IK LeVan, TR Spraker, MW Miller, and SL Quackenbush (2016).
Experimental Transmission of Bighorn Sheep Sinus Tumors to Bighorn Sheep (Ovis canadensis canadensis) and
Domestic Sheep. Veterinary Pathology 53(6):1164-1171.
Fox KA, NM Rouse, KP Huyvaert, KA Griffin, HJ Killion, JJ Gaines, WH Edwards, SL Quackenbush, and MW Miller
(2015). Bighorn Sheep Sinus Tumors are Associated with Co-infections by Potentially Pathogenic Bacteria in the
Upper Respiratory Tract. Journal of Wildlife Diseases 51(1):19-27.
Fox KA, SK Wootton, SL Quackenbush, LL Wolfe, IK LeVan, MW Miller, and TR Spraker (2011). Paranasal Sinus
Masses of Rocky Mountain Bighorn Sheep (Ovis canadensis canadensis). Veterinary Pathology 48(3):706-12.
Rev 12/2019

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