Complex evolutionary history of felid anelloviruses

Item Metadata

Dublin Core

Title

Complex evolutionary history of felid anelloviruses

Description

Anellovirus infections are highly prevalent in mammals, however, prior to this study only a handful of anellovirus genomes had been identified in members of the Felidae family. Here we characterise anelloviruses in pumas (Puma concolor), bobcats (Lynx rufus), Canada lynx (Lynx canadensis), caracals (Caracal caracal) and domestic cats (Felis catus). The complete anellovirus genomes (n = 220) recovered from 149 individuals were diverse. ORF1 protein sequence similarity network  coupled with phylogenetic analysis, revealed two distinct clusters that are populated by felid-derived anellovirus sequences, a pattern mirroring that observed for the porcine anelloviruses. Of the two-felid dominant anellovirus groups, one includes sequences from bobcats, pumas, domestic cats and an ocelot, and the other includes sequences from caracals, Canada lynx, domestic cats and pumas. Coinfections of diverse anelloviruses appear to be common among the felids. Evidence of recombination, both within and between felid-specific anellovirus groups, supports a long coevolution history between host and virus.

Bibliographic Citation

Kraberger, S., L. E. K. Serieys, C. Richet, N. M. Fountain-Jones, G. Baele, J. M. Bishop, M. Nehring, J. S. Ivan, E. S. Newkirk, J. R. Squires, M. C. Lund, S. P. D. Riley, C. C. Wilmers, P. D. van Helden, K. Van Doorslaer, M. Culver, S. VandeWoude, D. P. Martin, and A. Varsani. 2021. Complex evolutionary history of felid anelloviruses. Virology 562:176–189. https://doi.org/10.1016/j.virol.2021.07.013

Creator

Kraberger, Simona
Serieys, Laurel E.K.
Richet, Cécile
Fountain-Jones, Nicholas M.
Baele, Guy
Bishop, Jacqueline M.
Nehring, Mary
Ivan, Jacob S.
Newkirk, Eric S.
Squires, John R.
Lund, Michael C.
Riley, Seth P.D.
Wilmers, Christopher C.
van Helden, Paul D.
Van Doorslaer, Koenraad
Culver, Melanie
VandeWoude, Sue
Martin, Darren P.
Varsani, Arvind

Subject

Bobcat
Puma
Caracal
Canada lynx
Domestic cat
Torque teno virus
Anelloviridae

Extent

14 pages

Date Created

2021-07-29

Type

Article

Format

application/pdf

Language

English

Is Part Of

Virology

Collection

Citation

Kraberger, Simona et al., “Complex evolutionary history of felid anelloviruses,” CPW Digital Collections, accessed February 27, 2024, https://cpw.cvlcollections.org/items/show/232.